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An Investigation of ReNu Knee Injection: Monitoring the Response of Knee Function and Pain in Patients with Osteoarthritis

ReNu is a randomized injection trial for patients with moderate knee osteoarthritis as determined by a combination of clinical and radiographic findings. Specifically, ReNu is an intra-articular injection of amniotic membrane and amniotic fluid cells, which have shown the potential to decrease inflammation and increase tissue healing in osteoarthritic patients. This trial will investigate the efficacy of this injection through a combination of patient-reported outcomes, physical exams, x-rays, and laboratory testing. Following the injection, patients will have follow-up visits at 1 week, 6 weeks, 3 months, 6 months, and 12 months. All patients participating in this trial will be randomized to receive ReNu, Hyaluronic, or a saline injection.

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If interested please contact:

Kavita Ahuja, Clinical Trial Co-ordinator:

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Elias Abousaad, Clinical Research Assistant:

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